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Issue 21, 2013
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Investigation of the electrical stability of Si-nanowire biologically sensitive field-effect transistors with embedded Ag/AgCl pseudo reference electrode

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Abstract

We report on the electrical stability of Si-nanowire biologically sensitive field-effect transistors (BioFETs) fabricated using conventional microfabrication technique, with an embedded Ag/AgCl pseudo-reference electrode (pRE) formed by an electrochemical method. The open-circuit potential (OCP) characteristics between the pRE and a commercial reference electrode have been measured in order to evaluate the influence of the pRE potential on the device performance. In a pH sensing mode, the fabricated pRE follows the applied potential accurately with a small offset value of below 6 mV for pH in the range of 4 to 10. The BioFET was also used for the detection of alpha fetoprotein (AFP) with a detection limit of 10 pg mL−1 and the corresponding OCP fluctuation of the pRE was less than 1.5 mV, independent of the AFP concentrations. These results suggest that the Si-NW BioFETs with the embedded Ag/AgCl pRE are very promising for reliable biosensing applications.

Graphical abstract: Investigation of the electrical stability of Si-nanowire biologically sensitive field-effect transistors with embedded Ag/AgCl pseudo reference electrode

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Publication details

The article was received on 13 Feb 2013, accepted on 15 Mar 2013 and first published on 15 Mar 2013


Article type: Paper
DOI: 10.1039/C3RA40768C
Citation: RSC Adv., 2013,3, 7963-7969
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    Investigation of the electrical stability of Si-nanowire biologically sensitive field-effect transistors with embedded Ag/AgCl pseudo reference electrode

    T. Rim, K. Kim, N. Hong, W. Ko, C. Baek, S. Jeon, M. J. Deen, M. Meyyappan, Y. Jeong and J. Lee, RSC Adv., 2013, 3, 7963
    DOI: 10.1039/C3RA40768C

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