Issue 2, 2013
From the journal:

RSC Advances

Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe – imaging and photodynamic therapy†

Tao Zhang,‡a   Chi-Fai Chan,‡ab   JianHua Hao,b   Ga-Lai Law,*c   Wai-Kwok Wong*a  and  Ka-Leung Wong*a  

* Corresponding authors

a Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong
E-mail: wkwong@hkbu.edu.hk, klwong@hkbu.edu.hk
Tel: +852 3411 2370

b Department of Physics, The Hong Kong Polytechnic University, Hong Hum, Hong Kong

c Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Hum, Hong Kong
E-mail: ga-lai.law@polyu.edu.hk

Abstract

A water-soluble, mitochondria-permeable erbium(III) complex has been designed as a responsive bi-functional probe. This may be used to induce the mild formation of singlet oxygen (ΦΔ = 0.10) and causes local damage in cellulo when exposed to UV and near-infrared laser excitation.

Graphical abstract: Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe – imaging and photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/C2RA22056C
Article type
Communication
Submitted
05 Sep 2012
Accepted
13 Nov 2012
First published
13 Nov 2012

RSC Adv., 2013,3, 382-385

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Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe – imaging and photodynamic therapy

T. Zhang, C. Chan, J. Hao, G. Law, W. Wong and K. Wong, RSC Adv., 2013, 3, 382 DOI: 10.1039/C2RA22056C

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