Issue 44, 2013
From the journal:

Organic & Biomolecular Chemistry

NaH mediated isomerisation–allylation reaction of 1,3-substituted propenols†

Adam J. S. Johnston,a   Mark G. McLaughlin,a   Jolene P. Reida  and  Matthew J. Cook*a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Queen's University Belfast, Belfast, Northern Ireland, UK
E-mail: m.cook@qub.ac.uk
Fax: +44 (0)28 90976524
Tel: +44 (0)28 90974682

Abstract

A base mediated isomerisation–allylation protocol of 1,3-disubstituted propenols has been established. The use of diaryl and aryl-silyl substrates is reported alongside the use of substituted allyl bromides. Mechanistic experiments have also been conducted to elucidate the reaction pathway.

Graphical abstract: NaH mediated isomerisation–allylation reaction of 1,3-substituted propenols

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3OB41857J
Article type
Communication
Submitted
11 Sep 2013
Accepted
03 Oct 2013
First published
03 Oct 2013
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2013,11, 7662-7666

Permissions

Request permissions

NaH mediated isomerisation–allylation reaction of 1,3-substituted propenols

A. J. S. Johnston, M. G. McLaughlin, J. P. Reid and M. J. Cook, Org. Biomol. Chem., 2013, 11, 7662 DOI: 10.1039/C3OB41857J

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements