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Issue 47, 2013
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A facile synthesis of 5-amino-[1,2,3]triazolo[5,1-a]isoquinoline derivatives through copper-catalyzed cascade reactions

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Abstract

A copper-catalyzed cascade method was developed for the synthesis of [1,2,3]triazolo[5,1-a]isoquinoline derivatives. The N-fused heterocycles were obtained in good to excellent yields under mild conditions, which provided a new strategy for the preparation of this highly functionalized building block.

Graphical abstract: A facile synthesis of 5-amino-[1,2,3]triazolo[5,1-a]isoquinoline derivatives through copper-catalyzed cascade reactions

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Publication details

The article was received on 30 Aug 2013, accepted on 30 Sep 2013 and first published on 30 Sep 2013


Article type: Communication
DOI: 10.1039/C3OB41774C
Citation: Org. Biomol. Chem., 2013,11, 8171-8174
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    A facile synthesis of 5-amino-[1,2,3]triazolo[5,1-a]isoquinoline derivatives through copper-catalyzed cascade reactions

    Y. Chen, S. Zhou, S. Ma, W. Liu, Z. Pan and X. Shi, Org. Biomol. Chem., 2013, 11, 8171
    DOI: 10.1039/C3OB41774C

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