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Issue 12, 2013
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Stereoselective synthesis of N-heterocycles through amine addition to nitroalkenes

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Abstract

An efficient route for the preparation of substituted N-heterocycles was developed through the amine addition to nitroalkenes. The reaction tolerates a large substrate scope with good to excellent yields (up to 95%) and excellent stereoselectivities (up to 99 : 1 dr).

Graphical abstract: Stereoselective synthesis of N-heterocycles through amine addition to nitroalkenes

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Publication details

The article was received on 18 Dec 2012, accepted on 25 Jan 2013 and first published on 28 Jan 2013


Article type: Communication
DOI: 10.1039/C3OB27452G
Citation: Org. Biomol. Chem., 2013,11, 1917-1920
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    Stereoselective synthesis of N-heterocycles through amine addition to nitroalkenes

    L. N. Gautam, Q. Wang, N. G. Akhmedov, J. L. Petersen and X. Shi, Org. Biomol. Chem., 2013, 11, 1917
    DOI: 10.1039/C3OB27452G

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