Jump to main content
Jump to site search

Issue 19, 2013
Previous Article Next Article

Carbohydrate-actuated nanofluidic diode: switchable current rectification in a nanopipette

Author affiliations

Abstract

Nanofluidic structures share many properties with ligand-gated ion channels. However, actuating ion conductance in artificial systems is a challenge. We have designed a system that uses a carbohydrate-responsive polymer to modulate ion conductance in a quartz nanopipette. The cationic polymer, a poly(vinylpyridine) quaternized with benzylboronic acid groups, undergoes a transition from swollen to collapsed upon binding to monosaccharides. As a result, the current rectification in nanopipettes can be reversibly switched depending on the concentration of monosaccharides. Such molecular actuation of nanofluidic conductance may be used in novel sensors and drug delivery systems.

Graphical abstract: Carbohydrate-actuated nanofluidic diode: switchable current rectification in a nanopipette

Back to tab navigation

Supplementary files

Publication details

The article was received on 27 Apr 2013, accepted on 29 Jul 2013 and first published on 02 Aug 2013


Article type: Paper
DOI: 10.1039/C3NR02105J
Citation: Nanoscale, 2013,5, 9214-9221
  •   Request permissions

    Carbohydrate-actuated nanofluidic diode: switchable current rectification in a nanopipette

    B. Vilozny, A. L. Wollenberg, P. Actis, D. Hwang, B. Singaram and N. Pourmand, Nanoscale, 2013, 5, 9214
    DOI: 10.1039/C3NR02105J

Search articles by author

Spotlight

Advertisements