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Issue 8, 2014
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The promotion of antimicrobial activity on silicon substrates using a “click” immobilized short peptide

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Abstract

We demonstrated, for the first time, that the short antimicrobial peptide Tet213 could be conjugated onto the silicon surface by Cu(I)-catalyzed azide–alkyne cycloaddition (CuAAC). The modified surface exhibited excellent antimicrobial activity against S. aureus and E. coli, and low cytotoxicity to rat bone mesenchymal stem cells (rBMSCs).

Graphical abstract: The promotion of antimicrobial activity on silicon substrates using a “click” immobilized short peptide

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Publication details

The article was received on 15 Oct 2013, accepted on 06 Nov 2013 and first published on 07 Nov 2013


Article type: Communication
DOI: 10.1039/C3CC47922F
Citation: Chem. Commun., 2014,50, 975-977
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    The promotion of antimicrobial activity on silicon substrates using a “click” immobilized short peptide

    L. Wang, J. Chen, L. Shi, Z. Shi, L. Ren and Y. Wang, Chem. Commun., 2014, 50, 975
    DOI: 10.1039/C3CC47922F

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