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Issue 6, 2013
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A controllable gene expression system in liposomes that includes a positive feedback loop

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Abstract

We introduced a positive feedback loop into a LacI-dependent gene expression system in lipid vesicles, producing a cell-like system that senses and responds to an external signal with a high signal-to-noise ratio. This fully reconstituted system will be a useful tool in future applications in in vitro synthetic biology.

Graphical abstract: A controllable gene expression system in liposomes that includes a positive feedback loop

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Publication details

The article was received on 23 Jan 2013, accepted on 12 Mar 2013 and first published on 12 Mar 2013


Article type: Communication
DOI: 10.1039/C3MB70032A
Citation: Mol. BioSyst., 2013,9, 1282-1285
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    A controllable gene expression system in liposomes that includes a positive feedback loop

    S. Kobori, N. Ichihashi, Y. Kazuta and T. Yomo, Mol. BioSyst., 2013, 9, 1282
    DOI: 10.1039/C3MB70032A

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