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Issue 4, 2014
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New technologies for measuring single cell mass

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Abstract

Characterizing the physical properties of single cells is of great interest for unraveling the heterogeneity in a cell population. Recent advances in micro-systems technologies and quantitative imaging have enabled measurements of the mass and growth of single cells. So far, three classes of techniques have been reported for such measurements. These are suspended micro-channel resonators (SMR) sensors, quantitative phase imaging (QPI), and pedestal resonant sensors. Here we compare the unique merits of each method and discuss their potential to evolve into multi-modal platforms for answering fundamental questions in biology and medicine.

Graphical abstract: New technologies for measuring single cell mass

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Publication details

The article was received on 09 Sep 2013, accepted on 19 Nov 2013 and first published on 19 Nov 2013


Article type: Focus
DOI: 10.1039/C3LC51033F
Citation: Lab Chip, 2014,14, 646-652
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    New technologies for measuring single cell mass

    G. Popescu, K. Park, M. Mir and R. Bashir, Lab Chip, 2014, 14, 646
    DOI: 10.1039/C3LC51033F

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