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Issue 14, 2013
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A microfluidic concentration-gradient droplet array generator for the production of multi-color nanoparticles

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Abstract

A microfluidic concentration-gradient droplet array generator (CDrAG) with parallel multi-channels and multi-layers was developed with 64 outlet channels producing 33 droplet gradient concentrations. A droplet production rate of 5 × 104 min−1 was obtained, and the RSD value of droplet diameters in 64 groups is 5.5% (n = 64). Using the concentration gradient droplet array as parallel microreactors, 33 Au/Ag ratio nanoparticles were synthesized. The absorption spectra of the Au/Ag nanoparticles shifted from the spectrum of pure gold to one of pure silver. This demonstrates the CDrAG platform's promising potential to produce specific nanoparticle barcodes for high-throughput screening in chemistry, biology and a broad range of life science applications.

Graphical abstract: A microfluidic concentration-gradient droplet array generator for the production of multi-color nanoparticles

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Publication details

The article was received on 22 Feb 2013, accepted on 17 Apr 2013 and first published on 17 Apr 2013


Article type: Paper
DOI: 10.1039/C3LC50254F
Citation: Lab Chip, 2013,13, 2815-2820
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    A microfluidic concentration-gradient droplet array generator for the production of multi-color nanoparticles

    C. Yang, Z. Xu, A. P. Lee and J. Wang, Lab Chip, 2013, 13, 2815
    DOI: 10.1039/C3LC50254F

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