Issue 8, 2013

Micro-optical lens array for fluorescence detection in droplet-based microfluidics

Abstract

We demonstrate the design and integration of droplet-based microfluidic devices with microoptical element arrays for enhanced detection of fluorescent signals. We show that the integration of microlenses and mirror surfaces in these devices results in an 8-fold increase in the fluorescence signal and in improved spatial resolution. Using an array of microlenses, massively parallel detection of droplets containing fluorescent dyes was achieved, leading to detection throughputs of about 2000 droplets per second and per lens, parallelized over 625 measurement points.

Graphical abstract: Micro-optical lens array for fluorescence detection in droplet-based microfluidics

Supplementary files

Article information

Article type
Technical Innovation
Submitted
04 Dec 2012
Accepted
29 Jan 2013
First published
30 Jan 2013
This article is Open Access
Creative Commons BY license

Lab Chip, 2013,13, 1472-1475

Micro-optical lens array for fluorescence detection in droplet-based microfluidics

J. Lim, P. Gruner, M. Konrad and J. Baret, Lab Chip, 2013, 13, 1472 DOI: 10.1039/C3LC41329B

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