Jump to main content
Jump to site search

Issue 41, 2013
Previous Article Next Article

Structure and stability studies of mixed monolayers of saturated and unsaturated phospholipids under low-level ozone

Author affiliations

Abstract

In the present study, stability and structure of single and binary mixed monolayers of an unsaturated phospholipid, DOPC, and a saturated phospholipid, DPPC-d75, on the water surface, were explored using the π–A isotherm, atomic force microscopy (AFM) and sum frequency generation (SFG) vibrational spectroscopy in various environments. Our results demonstrated that DOPC in the monolayers becomes unstable after the exposure to a low concentration of ozone (20 ± 10 ppb) or even to ambient laboratory air, which has a similar ozone level, but is stable in nitrogen or oxygen. DOPC can be selectively oxidized by a trace amount of ozone in the ambient environment but can be partially inhibited by the presence of DPPC in the monolayer. The present study provides useful information for understanding the physicochemical properties of the cell membranes.

Graphical abstract: Structure and stability studies of mixed monolayers of saturated and unsaturated phospholipids under low-level ozone

Back to tab navigation

Supplementary files

Publication details

The article was received on 14 Jun 2013, accepted on 12 Aug 2013 and first published on 19 Aug 2013


Article type: Paper
DOI: 10.1039/C3CP52484A
Citation: Phys. Chem. Chem. Phys., 2013,15, 17775-17785
  •   Request permissions

    Structure and stability studies of mixed monolayers of saturated and unsaturated phospholipids under low-level ozone

    L. Qiao, A. Ge, M. Osawa and S. Ye, Phys. Chem. Chem. Phys., 2013, 15, 17775
    DOI: 10.1039/C3CP52484A

Search articles by author

Spotlight

Advertisements