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Issue 26, 2014
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Modulation of raft domains in a lipid bilayer by boundary-active curcumin

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Abstract

The function and mode of action of curcumin in modulating the formation of lipid raft domains were investigated by microscopic observation using model membranes. Curcumin induces fusion of lipid raft domains at extremely low concentrations through the alteration of the boundary between the ordered and disordered phases.

Graphical abstract: Modulation of raft domains in a lipid bilayer by boundary-active curcumin

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Publication details

The article was received on 08 Oct 2013, accepted on 16 Dec 2013 and first published on 16 Dec 2013


Article type: Communication
DOI: 10.1039/C3CC47738J
Citation: Chem. Commun., 2014,50, 3427-3430
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    Modulation of raft domains in a lipid bilayer by boundary-active curcumin

    M. Tsukamoto, K. Kuroda, A. Ramamoorthy and K. Yasuhara, Chem. Commun., 2014, 50, 3427
    DOI: 10.1039/C3CC47738J

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