Issue 85, 2013

A non-nucleoside triphosphate for powering kinesin-microtubule motility with photo-tunable velocity

Abstract

Three non-nucleoside triphosphates, one containing an azobenzene moiety, power a kinesin-microtubule system with high motile activity, with an observed maximum velocity of almost half of that obtained with ATP. The cistrans photoisomerization of the azobenzene unit allows reversible and repeated control over the motile properties of kinesin.

Graphical abstract: A non-nucleoside triphosphate for powering kinesin-microtubule motility with photo-tunable velocity

Supplementary files

Article information

Article type
Communication
Submitted
03 Aug 2013
Accepted
30 Aug 2013
First published
30 Aug 2013

Chem. Commun., 2013,49, 9935-9937

A non-nucleoside triphosphate for powering kinesin-microtubule motility with photo-tunable velocity

N. Perur, M. Yahara, T. Kamei and N. Tamaoki, Chem. Commun., 2013, 49, 9935 DOI: 10.1039/C3CC45933K

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