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Issue 61, 2013
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Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

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Abstract

A DNA molecule is rotated under a transversal electric field to be perpendicular to a longitudinal, multicomponent microfluidic flow. Positioning the interface allows us to control DNA unzipping with spatio-temporal resolution. This demonstrates that a microfluidic gradient can be applied at the single molecule level for a dynamic intramolecular stimulation.

Graphical abstract: Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

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Publication details

The article was received on 28 May 2013, accepted on 10 Jun 2013, published on 11 Jun 2013 and first published online on 11 Jun 2013


Article type: Communication
DOI: 10.1039/C3CC44016H
Citation: Chem. Commun., 2013,49, 6858-6860
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    Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

    N. K. Mani, S. Rudiuk and D. Baigl, Chem. Commun., 2013, 49, 6858
    DOI: 10.1039/C3CC44016H

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