Issue 52, 2013

Species selective diazirine positioning in tag-free photoactive quorum sensing probes

Abstract

The synthesis and comparison of activities of ‘tag-free’ probes with diazirines at various positions are described. Remarkable differences in their effects on P. aeruginosa and on human bronchial epithelial cells were observed, supporting the efforts to isolate and identify receptors for N-acyl homoserine lactones.

Graphical abstract: Species selective diazirine positioning in tag-free photoactive quorum sensing probes

Supplementary files

Article information

Article type
Communication
Submitted
26 Apr 2013
Accepted
08 May 2013
First published
10 May 2013

Chem. Commun., 2013,49, 5826-5828

Species selective diazirine positioning in tag-free photoactive quorum sensing probes

L. Dubinsky, A. Delago, N. Amara, P. Krief, J. Rayo, T. Zor, V. V. Kravchenko and M. M. Meijler, Chem. Commun., 2013, 49, 5826 DOI: 10.1039/C3CC43092H

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