Issue 31, 2013
From the journal:

Chemical Communications

Palladium-catalyzed insertion of N-tosylhydrazones for the synthesis of isoindolines†

Ping-Xin Zhou,a   Jian-Yi Luo,a   Lian-Biao Zhao,b   Yu-Ying Yea  and  Yong-Min Liang*a  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China
E-mail: liangym@lzu.edu.cn
Fax: +86-931-8912582

b College of Chemical Engineering, Northwest University for Nationalities, Lanzhou 730030, China

Abstract

Isoindolines are synthesized by palladium-catalyzed coupling reaction of N-(2-iodobenzyl) anilines with α,β-unsaturated N-tosylhydrazones. The reaction has several potential advantages: (1) toleration of a wide range of functional groups, (2) easy to handle and with mild conditions, (3) enriches the isoindoline family, (4) two new bonds form in one step.

Graphical abstract: Palladium-catalyzed insertion of N-tosylhydrazones for the synthesis of isoindolines

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC40577J
Article type
Communication
Submitted
23 Jan 2013
Accepted
27 Feb 2013
First published
28 Feb 2013

Chem. Commun., 2013,49, 3254-3256

Permissions

Request permissions

Palladium-catalyzed insertion of N-tosylhydrazones for the synthesis of isoindolines

P. Zhou, J. Luo, L. Zhao, Y. Ye and Y. Liang, Chem. Commun., 2013, 49, 3254 DOI: 10.1039/C3CC40577J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements