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Issue 4, 2013
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DNA origami technology for biomaterials applications

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Abstract

DNA origami is an emerging technology for designing and constructing defined multidimensional nanostructures. This technology is now expanding to materials science. This article introduces the basics of DNA origami, the design of various two-dimensional and three-dimensional DNA origami structures, and the programmed assembly of origami structures. DNA origami has unique properties, such as an addressable surface, which enables selective functionalization with biomolecules and nanomaterials. The origami can also be combined with top-down nanotechnology, such as placement on a fabricated substrate. The technology is also applied to single-molecule imaging and analysis systems constructed on designed DNA origami structures. Furthermore, DNA mechanical nanodevices working on DNA origami have been realized, and cell-oriented applications are now in progress. DNA origami technology has practical potential in various research fields.

Graphical abstract: DNA origami technology for biomaterials applications

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Publication details

The article was received on 20 Oct 2012, accepted on 12 Nov 2012 and first published on 07 Dec 2012


Article type: Review Article
DOI: 10.1039/C2BM00154C
Citation: Biomater. Sci., 2013,1, 347-360
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    DNA origami technology for biomaterials applications

    M. Endo, Y. Yang and H. Sugiyama, Biomater. Sci., 2013, 1, 347
    DOI: 10.1039/C2BM00154C

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