Issue 5, 2013
From the journal:

Analytical Methods

Colorimetric anticancer drug detection by gold nanoparticle-based DNA interstrand cross-linking†

Xiaoji Xie,a   Renren Deng,a   Feng Liu,a   Wei Xu,a   Sam Fong Yau Li*ab  and  Xiaogang Liu*ac  

* Corresponding authors

a Department of Chemistry, Faculty of Science, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
E-mail: chmlx@nus.edu.sg, chmlifys@nus.edu.sg

b NUS Environmental Research Institute, National University of Singapore, 5A Engineering Drive 1, Singapore 117411, Singapore

c Institute of Materials Research and Engineering, 3, Research Link, Singapore 117602, Singapore

Abstract

A low-cost, convenient approach, based on gold nanoparticles and DNA interstrand cross-linking has been developed for rapid colorimetric detection of anticancer drugs. This method also provides insight into the controlled assembly of DNA superstructures.

Graphical abstract: Colorimetric anticancer drug detection by gold nanoparticle-based DNA interstrand cross-linking

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Article information

DOI
https://doi.org/10.1039/C3AY26422J
Article type
Communication
Submitted
19 Nov 2012
Accepted
12 Jan 2013
First published
24 Jan 2013

Anal. Methods, 2013,5, 1116-1119

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Colorimetric anticancer drug detection by gold nanoparticle-based DNA interstrand cross-linking

X. Xie, R. Deng, F. Liu, W. Xu, S. F. Yau Li and X. Liu, Anal. Methods, 2013, 5, 1116 DOI: 10.1039/C3AY26422J

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