Issue 13, 2013
From the journal:

Analyst

A label-free amplified fluorescence DNA detection based on isothermal circular strand-displacement polymerization reaction and graphene oxide†

Zhen Li,a   Wenping Zhu,a   Jinwen Zhang,a   Jianhui Jiang,*a   Guoli Shena  and  Ruqin Yu*a  

* Corresponding authors

a State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, P. R. China
E-mail: jianhuijiang@hnu.edu.cn, rqyu@hnu.edu.cn
Fax: +86-731-8822782
Tel: +86-731-8822577

Abstract

A label-free fluorescent DNA biosensor has been presented based on isothermal circular strand-displacement polymerization reaction (ICSDPR) combined with graphene oxide (GO) binding. The proposed method is simple and cost-effective with a low detection limit of 4 pM, which compares favorably with other GO-based homogenous DNA detection methods.

Graphical abstract: A label-free amplified fluorescence DNA detection based on isothermal circular strand-displacement polymerization reaction and graphene oxide

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Article information

DOI
https://doi.org/10.1039/C3AN00421J
Article type
Communication
Submitted
01 Mar 2013
Accepted
30 Apr 2013
First published
30 Apr 2013

Analyst, 2013,138, 3616-3620

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A label-free amplified fluorescence DNA detection based on isothermal circular strand-displacement polymerization reaction and graphene oxide

Z. Li, W. Zhu, J. Zhang, J. Jiang, G. Shen and R. Yu, Analyst, 2013, 138, 3616 DOI: 10.1039/C3AN00421J

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