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Issue 1, 2013
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Electrogenerated chemiluminescence of nanomaterials for bioanalysis

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Abstract

Since the electrogenerated chemiluminescence (ECL) of silicon nanoparticles (NPs) was reported in 2002, miscellaneous nanomaterials with various sizes and shapes have been employed as ECL nanoemitters for bioanalysis. Elucidation of the ECL derivation from these nanoemitters and pertinent biofunctionalization with multitudinous biomolecules can offer excellent ECL signal-transduction platforms for fabricating novel biosensing devices. In this review, we comprehensively describe retrospective and recent advances in NPs-based ECL and related biosensing methodologies, and review their analytical applications in the detection of small biological molecules, enzymatic sensing, immunoassay, DNA analysis and cytosensing.

Graphical abstract: Electrogenerated chemiluminescence of nanomaterials for bioanalysis

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Publication details

The article was received on 14 Aug 2012, accepted on 24 Sep 2012 and first published on 26 Sep 2012


Article type: Critical Review
DOI: 10.1039/C2AN36122A
Citation: Analyst, 2013,138, 43-61
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    Electrogenerated chemiluminescence of nanomaterials for bioanalysis

    S. Deng and H. Ju, Analyst, 2013, 138, 43
    DOI: 10.1039/C2AN36122A

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