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Edge Article

End-to-end continuous flow synthesis and purification of diphenhydramine hydrochloride featuring atom economy, in-line separation, and flow of molten ammonium salts

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Massachusetts Institute of Technology, Department of Chemistry, 77 Massachusetts Ave., Cambridge, USA
E-mail: tfj@mit.edu ;
Tel: +1 617 253-2135
Chem. Sci., 2013,4, 2822-2827

DOI: 10.1039/C3SC50859E
Received 29 Mar 2013, Accepted 14 May 2013
First published online 21 May 2013
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