Issue 11, 2013
From the journal:

RSC Advances

Biodegradable polymer network encapsulated polyplex for DNA delivery†

Petar D. Petrov,*a   Nadya I. Ivanova,b   Margarita D. Apostolovab  and  Christo B. Tsvetanova  

* Corresponding authors

a Institute of Polymers, Bulgarian Academy of Sciences, “Akad. G. Bonchev” Street 103A, 1113 Sofia, Bulgaria
E-mail: ppetrov@polymer.bas.bg
Fax: +35928700309
Tel: +35929796335

b Institute of Molecular Biology “Roumen Tsanev”, Bulgarian Academy of Sciences, “Acad. Georgi Bonchev” str., bl. 21, Sofia, Bulgaria
E-mail: margo@obzor.bio21.bas.bg
Fax: +35928723507
Tel: +3592 979 3684

Abstract

A novel gene delivery system is made by encapsulation of a polyplex between pDNA and cationic micelles with a biodegradable crosslinked shell. The outer shell can provide additional functionality to the system and protect DNA from degradation. The encapsulated polyplex exhibits a similar transfection efficiency compared to the naked polyplex.

Graphical abstract: Biodegradable polymer network encapsulated polyplex for DNA delivery

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3RA21890B
Article type
Communication
Submitted
22 Aug 2012
Accepted
11 Jan 2013
First published
14 Jan 2013

RSC Adv., 2013,3, 3508-3511

Permissions

Request permissions

Biodegradable polymer network encapsulated polyplex for DNA delivery

P. D. Petrov, N. I. Ivanova, M. D. Apostolova and C. B. Tsvetanov, RSC Adv., 2013, 3, 3508 DOI: 10.1039/C3RA21890B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements