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MedChemComm

Research and review articles in medicinal chemistry and related drug discovery science; the official journal of the European Federation for Medicinal Chemistry

Concise Article

Design of potential bisubstrate inhibitors against Mycobacterium tuberculosis (Mtb) 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Dxr)—evidence of a novel binding mode

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Corresponding authors
a
Department of Chemistry, George Washington University, Washington, USA
E-mail: cdowd@gwu.edu
Fax: +1 202 994 5873
Tel: +1 202 994 8405
b
Department of Chemistry and Biochemistry, George Mason University, Manassas, USA
E-mail: rcouch@gmu.edu
Fax: +1 703 993 8430
Tel: +1 703 993 4770
c
National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, USA
E-mail: kkhall@gmu.edu
Fax: +1 703 993 4280
Tel: +1 703 993 8869
d
Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, USA
E-mail: hboshoff@niaid.nih.gov
Fax: +1 301 480 5705
Tel: +1 301 451 9438
Med. Chem. Commun., 2013,4, 1099-1104

DOI: 10.1039/C3MD00085K
Received 14 Mar 2013, Accepted 28 May 2013
First published online 29 May 2013
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