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Issue 38, 2013
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Protein-coated nanofibers for promotion of T cell activity

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Abstract

We have demonstrated that stable Concanavalin A (Con A)-coated supramolecular nanofibers can be constructed by complexation of self-assembled mannose nanofibers with Con A. The extended multivalent Con A nanofibers bind strongly to T cell surfaces and promote T cell activation.

Graphical abstract: Protein-coated nanofibers for promotion of T cell activity

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Publication details

The article was received on 15 Feb 2013, accepted on 22 Mar 2013 and first published on 22 Mar 2013


Article type: Communication
DOI: 10.1039/C3CC41215F
Citation: Chem. Commun., 2013,49, 3949-3951
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    Protein-coated nanofibers for promotion of T cell activity

    T. Kim, H. Lee, Y. Kim, J. Nam and M. Lee, Chem. Commun., 2013, 49, 3949
    DOI: 10.1039/C3CC41215F

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