Jump to main content
Jump to site search

Issue 36, 2012
Previous Article Next Article

Theory of DNA–cationic micelle complexation

Author affiliations

Abstract

We present a theory of spherical micelle formation from cationic amphiphiles in the absence and in the presence of DNA. The distribution of micelle sizes as well as the critical micelle and aggregation concentrations (cmc and cac) are calculated. Micelle formation is favored by the hydrophobic tails but disfavored by the entropic cost associated with counterion condensation. Counterion release drives the complexation between DNA and amphiphiles and causes micellation at a much smaller concentration than in the absence of DNA. The stiffness of double-stranded DNA favors the formation of large micelles leading to a bimodal distribution of micelle sizes.

Graphical abstract: Theory of DNA–cationic micelle complexation

Back to tab navigation

Publication details

The article was received on 15 Mar 2012, accepted on 03 Jul 2012 and first published on 23 Jul 2012


Article type: Paper
DOI: 10.1039/C2SM25603G
Citation: Soft Matter, 2012,8, 9406-9411
  •   Request permissions

    Theory of DNA–cationic micelle complexation

    H. Schiessel, M. D. Correa-Rodríguez, S. Rudiuk, D. Baigl and K. Yoshikawa, Soft Matter, 2012, 8, 9406
    DOI: 10.1039/C2SM25603G

Search articles by author

Spotlight

Advertisements