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Issue 10, 2012
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Reversible regulation of bioactive ligands presented on immobilized gold nanoparticles

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Abstract

A polypeptide fusion of a bioactive ligand and a coiled-coil A was functionalized on gold nanoparticles, which were subsequently immobilized on substrates. The accessibility of the ligand could be reversibly controlled via co-immobilization and removal of B-poly(ethylene) glycol through heterodimerization between A and the complementary coiled-coil B.

Graphical abstract: Reversible regulation of bioactive ligands presented on immobilized gold nanoparticles

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Publication details

The article was received on 16 Aug 2011, accepted on 06 Jan 2012 and first published on 01 Feb 2012


Article type: Communication
DOI: 10.1039/C2SM06567C
Citation: Soft Matter, 2012,8, 2812-2815
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    Reversible regulation of bioactive ligands presented on immobilized gold nanoparticles

    X. Wang, J. J. Riesberg and W. Shen, Soft Matter, 2012, 8, 2812
    DOI: 10.1039/C2SM06567C

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