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Issue 16, 2012
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Programmed size-selected permeation of ssDNA into ZnS mesoporous hollow spheres

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Abstract

The permeability of liquid crystal templated ZnS mesoporous hollow spheres is programmed and investigated with molecular probes. Pore size programming was achieved by swelling of the hydrophobic regions of the lyotropic liquid crystal used to template the mesoporous shell. Small angle X-ray scattering and transmission electron microscopy confirm that the mesopore diameter can be tuned between 2.5 and 4.1 nm. Predictions of the mesopore permeability of ssDNA from Flory scaling theory inspire the selection of fluorescently tagged ssDNA probes. Short ssDNA strands were found to easily penetrate the mesoporous shell, while large strands were excluded. Intermediate length ssDNA strands were able to penetrate shells with 4.1 nm mesopores, while being sterically excluded from 2.5 nm mesopores.

Graphical abstract: Programmed size-selected permeation of ssDNA into ZnS mesoporous hollow spheres

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Publication details

The article was received on 08 Jan 2012, accepted on 21 Feb 2012 and first published on 02 Mar 2012


Article type: Paper
DOI: 10.1039/C2SM00053A
Citation: Soft Matter, 2012,8, 4396-4401
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    Programmed size-selected permeation of ssDNA into ZnS mesoporous hollow spheres

    D. Van Gough, J. L. Defino and P. V. Braun, Soft Matter, 2012, 8, 4396
    DOI: 10.1039/C2SM00053A

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