Issue 10, 2012
From the journal:

Organic & Biomolecular Chemistry

Palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile: an efficient pathway for the synthesis of diverse 11H-indeno[1,2-c]quinolines†

Xiaolin Pan,a   Yong Luoa  and  Jie Wu*ab  

* Corresponding authors

a Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China
E-mail: jie_wu@fudan.edu.cn
Fax: +86 21 6564 1740
Tel: +86 21 6510 2412

b Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science & Technology Normal University, Nanchang 330013, China

Abstract

Diverse 11H-indeno[1,2-c]quinolines are produced via a palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile. This conversion tolerates a wide variety of functionality and substitution patterns on the 11H-indeno[1,2-c]quinoline ring.

Graphical abstract: Palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile: an efficient pathway for the synthesis of diverse 11H-indeno[1,2-c]quinolines

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Article information

DOI
https://doi.org/10.1039/C2OB06764A
Article type
Paper
Submitted
20 Oct 2011
Accepted
13 Dec 2011
First published
13 Dec 2011

Org. Biomol. Chem., 2012,10, 1969-1975

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Palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile: an efficient pathway for the synthesis of diverse 11H-indeno[1,2-c]quinolines

X. Pan, Y. Luo and J. Wu, Org. Biomol. Chem., 2012, 10, 1969 DOI: 10.1039/C2OB06764A

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