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Issue 11, 2012
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Bioactive natural products from Lysobacter

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Abstract

Covering: up to March 2012

The gliding Gram-negative Lysobacter bacteria are emerging as a promising source of new bioactive natural products. These ubiquitous freshwater and soil microorganisms are fast growing, simple to use and maintain, and genetically amenable for biosynthetic engineering. This Highlight reviews a group of biologically active and structurally distinct natural products from the genus Lysobacter, with a focus on their biosyntheses. Although Lysobacter sp. are known as prolific producers of bioactive natural products, detailed molecular mechanistic studies of their enzymatic assembly have been surprisingly scarce. We hope to provide a snapshot of the important work done on the lysobacterial natural products and to provide useful information for future biosynthetic engineering of novel antibiotics in Lysobacter.

Graphical abstract: Bioactive natural products from Lysobacter

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Publication details

The article was received on 30 May 2012 and first published on 17 Aug 2012


Article type: Highlight
DOI: 10.1039/C2NP20064C
Citation: Nat. Prod. Rep., 2012,29, 1277-1287
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    Bioactive natural products from Lysobacter

    Y. Xie, S. Wright, Y. Shen and L. Du, Nat. Prod. Rep., 2012, 29, 1277
    DOI: 10.1039/C2NP20064C

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