This communication presents the concept of “deterministic cell rolling”, which leverages transient cell-surface molecular interactions that mediate cell rolling to sort cells with high purity and efficiency in a single step.
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Cell sorting by deterministic cell rolling
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a
Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge
E-mail: karnik@mit.edu ;
Fax: +617-258-9346 ;
Tel: +617-324-1155
E-mail: karnik@mit.edu ;
Fax: +617-258-9346 ;
Tel: +617-324-1155
b
Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Harvard-MIT Division of Health Sciences and Technology, Cambridge
E-mail: jkarp@rics.bwh.harvard.edu ;
Fax: +617-768-8338 ;
Tel: +617-817-9174
E-mail: jkarp@rics.bwh.harvard.edu ;
Fax: +617-768-8338 ;
Tel: +617-817-9174
Lab Chip, 2012,12, 1427-1430
DOI: 10.1039/C2LC21225K
Received 09 Dec 2011, Accepted 30 Jan 2012
First published online 10 Feb 2012
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