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Issue 7, 2012
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High sensitivity three-dimensional insulator-based dielectrophoresis

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Insulator-based dielectrophoresis (iDEP) is a very promising technique for sorting microparticles based on their electrical properties. The need for microfabricated electrode arrays is eliminated by using constrictions in a microchannel to induce large electric field gradients. In this work, micro-milling is used to build devices with three-dimensional features that exhibit very large constriction ratios. These three-dimensional insulator-based dielectrophoresis (3DiDEP) devices allow for trapping microparticles at average electric fields one order of magnitude lower than two-dimensional designs with the same footprint. Low voltage operation minimizes Joule heating effects that have limited previous systems, opening up the possibility for new biological applications of iDEP.

Graphical abstract: High sensitivity three-dimensional insulator-based dielectrophoresis

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Publication details

The article was received on 06 Dec 2011, accepted on 14 Dec 2011 and first published on 07 Feb 2012

Article type: Paper
DOI: 10.1039/C2LC21212A
Citation: Lab Chip, 2012,12, 1327-1331
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    High sensitivity three-dimensional insulator-based dielectrophoresis

    W. A. Braff, A. Pignier and C. R. Buie, Lab Chip, 2012, 12, 1327
    DOI: 10.1039/C2LC21212A

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