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Integrative Biology

Interdisciplinary approaches for molecular and cellular life sciences

Paper

Mechanical compaction directly modulates the dynamics of bile canaliculi formation

Yan Wang,*abc   Yi-Chin Toh,*a   Qiushi Li,ad   Bramasta Nugraha,ae   Baixue Zheng,adf   Thong Beng Lu,g   Yi Gao,b   Mary Mah Lee Ngg and   Hanry Yuacdfghij  
*
Corresponding authors
a
Institute of Bioengineering and Nanotechnology, A*STAR, #04-01, 31 Biopolis Way, Singapore 138669, Singapore
E-mail: yctoh@ibn.a-star.edu.sg
b
Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China
E-mail: yanwang@fimmu.com
Fax: +86 2061643010
c
Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, MD 9 #03-03, 2 Medical Drive, Singapore 117597, Singapore
d
Mechanobiology Institute, Temasek Laboratories, National University of Singapore, #05-01, 5A Engineering Drive 1, Singapore 117411, Singapore
e
NUS Graduate School for Integrative Sciences and Engineering, Centre for Life Sciences (CeLS), #05-01, 28 Medical Drive, Singapore 117456, Singapore
f
Singapore-MIT Alliance, National University of Singapore, E4 #04-10, 4 Engineering Drive 3, Singapore 117576, Singapore
g
Electron Microscopy Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore
h
Singapore-MIT Alliance Research and Technology, National University of Singapore, S16-05-08, 3 Science Drive 2, Singapore 117543, Singapore
i
NUS Tissue-Engineering Program, DSO Labs, National University of Singapore, Singapore 117597, Singapore
j
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, USA
Integr. Biol., 2013,5, 390-401

DOI: 10.1039/C2IB20229H
Received 27 Sep 2012, Accepted 20 Nov 2012
First published online 26 Nov 2012
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