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Issue 13, 2013
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Multiplexed surface micropatterning of proteins with a pressure-modulated microfluidic button-membrane

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Abstract

We report the flow-based in situ patterning of multiple proteins in microfluidic channels by simply tuning the actuation pressure of a microfluidic button-membrane. We show that a single button-membrane can pattern several concentric protein annuli, and we apply this patterning approach to a multiplexed immunoassay.

Graphical abstract: Multiplexed surface micropatterning of proteins with a pressure-modulated microfluidic button-membrane

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Publication details

The article was received on 24 Oct 2012, accepted on 15 Nov 2012 and first published on 16 Nov 2012


Article type: Communication
DOI: 10.1039/C2CC37740C
Citation: Chem. Commun., 2013,49, 1264-1266
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    Multiplexed surface micropatterning of proteins with a pressure-modulated microfluidic button-membrane

    J. L. Garcia-Cordero and S. J. Maerkl, Chem. Commun., 2013, 49, 1264
    DOI: 10.1039/C2CC37740C

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