Issue 84, 2012
From the journal:

Chemical Communications

Real-time monitoring biomarker expression of carcinoma cells by surface plasmon resonance biosensors†

Chang Liu,a   Tingjun Lei,b   Kosuke Ino,c   Tomokazu Matsue,c   Nongjian Taod  and  Chen-Zhong Li*a  

* Corresponding authors

a Nanobioengineering/Nanobioelectronics Laboratory, Department of Biomedical Engineering, Florida International University, 10555 W Flagler Street, Miami, USA
E-mail: licz@fiu.edu
Fax: +1 305 348 6954
Tel: +1 305 348 0120

b Biotransport Laboratory, Department of Biomedical Engineering, Florida International University, 10555 W Flagler Street, Miami, USA

c Graduate School of Environmental Studies, Tohoku University, 6-6-11-605 Aramaki, Aoba, Japan

d Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, USA

Abstract

A novel surface plasmon resonance (SPR) biosensor which is capable of monitoring proteomic biomarker secretion from living cells is reported here. Vascular endothelial growth factor (VEGF) secretion from living SKOV-3 ovarian cancer cells was measured for concept demonstration.

Graphical abstract: Real-time monitoring biomarker expression of carcinoma cells by surface plasmon resonance biosensors

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Article information

DOI
https://doi.org/10.1039/C2CC34853E
Article type
Communication
Submitted
07 Jul 2012
Accepted
26 Aug 2012
First published
06 Sep 2012

Chem. Commun., 2012,48, 10389-10391

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Real-time monitoring biomarker expression of carcinoma cells by surface plasmon resonance biosensors

C. Liu, T. Lei, K. Ino, T. Matsue, N. Tao and C. Li, Chem. Commun., 2012, 48, 10389 DOI: 10.1039/C2CC34853E

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