Issue 65, 2012
From the journal:

Chemical Communications

pH-triggered blooming of ‘nano-flowers’ for tumor intracellular drug delivery†

Zhefan Yuan,a   Zhenyang Que,a   Sixue Cheng,a   Renxi Zhuoa  and  Feng Li*a  

* Corresponding authors

a Polymers of Ministry of Education, College of Chemistry and Molecular Science, Wuhan University, Wuhan, P. R. China
E-mail: lfsj2004@hotmail.com

Abstract

With the decrease in pH value, the ‘nano-flower’ exhibited a half-open state to expose the target ligands on the surface under tumor acidic conditions and fully bloomed to release Dox under endosomal acidic conditions.

Graphical abstract: pH-triggered blooming of ‘nano-flowers’ for tumor intracellular drug delivery

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Article information

DOI
https://doi.org/10.1039/C2CC34225A
Article type
Communication
Submitted
13 Jun 2012
Accepted
27 Jun 2012
First published
27 Jun 2012

Chem. Commun., 2012,48, 8129-8131

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pH-triggered blooming of ‘nano-flowers’ for tumor intracellular drug delivery

Z. Yuan, Z. Que, S. Cheng, R. Zhuo and F. Li, Chem. Commun., 2012, 48, 8129 DOI: 10.1039/C2CC34225A

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