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Issue 44, 2012
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Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters

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Abstract

A simple NaOMe catalyst provides superior accessibility to a wide variety of functionalized amides including peptides through direct amination of esters in an atom-economical and environmentally benign way.

Graphical abstract: Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters

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Publication details

The article was received on 24 Mar 2012, accepted on 12 Apr 2012 and first published on 12 Apr 2012


Article type: Communication
DOI: 10.1039/C2CC32153J
Citation: Chem. Commun., 2012,48, 5434-5436
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    Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters

    T. Ohshima, Y. Hayashi, K. Agura, Y. Fujii, A. Yoshiyama and K. Mashima, Chem. Commun., 2012, 48, 5434
    DOI: 10.1039/C2CC32153J

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