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Issue 38, 2012
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Enantioselective organocatalytic reductive amination of aliphatic ketones by benzothiazoline as hydrogen donor

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Abstract

The chiral phosphoric acid-catalyzed enantioselective reductive amination of aliphatic ketones with aromatic amines was successfully achieved by the use of benzothiazoline as the hydrogen donor. Corresponding chiral aliphatic amines were obtained with excellent enantioselectivities.

Graphical abstract: Enantioselective organocatalytic reductive amination of aliphatic ketones by benzothiazoline as hydrogen donor

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Publication details

The article was received on 28 Feb 2012, accepted on 17 Mar 2012 and first published on 19 Mar 2012


Article type: Communication
DOI: 10.1039/C2CC31486J
Citation: Chem. Commun., 2012,48, 4573-4575
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    Enantioselective organocatalytic reductive amination of aliphatic ketones by benzothiazoline as hydrogen donor

    K. Saito and T. Akiyama, Chem. Commun., 2012, 48, 4573
    DOI: 10.1039/C2CC31486J

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