Issue 18, 2012

Regioselectivity among six secondary hydroxyl groups: selective acylation of the least reactive hydroxyl groups of inositol

Abstract

We report the first, general and selective acylation of the least reactive hydroxyl group among six secondary hydroxyl groups of inositol in high yield, using very cheap and easy-to-make H2SO4silica as the catalyst, providing easy access to bioactive molecules.

Graphical abstract: Regioselectivity among six secondary hydroxyl groups: selective acylation of the least reactive hydroxyl groups of inositol

Supplementary files

Article information

Article type
Communication
Submitted
21 Nov 2011
Accepted
06 Jan 2012
First published
10 Jan 2012

Chem. Commun., 2012,48, 2448-2450

Regioselectivity among six secondary hydroxyl groups: selective acylation of the least reactive hydroxyl groups of inositol

A. M. Vibhute, A. Vidyasagar, S. Sarala and K. M. Sureshan, Chem. Commun., 2012, 48, 2448 DOI: 10.1039/C2CC17241K

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