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Issue 22, 2012
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Dual-functional probes towards in vivo studies of brain connectivity and plasticity

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Abstract

A Gd3+ based paramagnetic dextran conjugate has been developed, which enables the tracking of neuroanatomical connectivity in the brain by both MR and optical imaging. Cell studies and subsequent in vivo experiments in rodents demonstrate efficient internalisation and transport properties of the new tracer molecule.

Graphical abstract: Dual-functional probes towards in vivo studies of brain connectivity and plasticity

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Publication details

The article was received on 26 Sep 2011, accepted on 10 Nov 2011 and first published on 01 Dec 2011


Article type: Communication
DOI: 10.1039/C1CC15991G
Citation: Chem. Commun., 2012,48, 2755-2757
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    Dual-functional probes towards in vivo studies of brain connectivity and plasticity

    I. Mamedov, J. Engelmann, O. Eschenko, M. Beyerlein and N. K. Logothetis, Chem. Commun., 2012, 48, 2755
    DOI: 10.1039/C1CC15991G

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