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Copper-catalyzed oxidative [2 + 2 + 1] cycloaddition: regioselective synthesis of 1,3-oxazoles from internal alkynes and nitriles

Xianwei Li,a   Liangbin Huang,a   Huoji Chen,a   Wanqing Wu,a   Huawen Huanga and   Huanfeng Jiang*a  
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School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, People’s Republic of China
Chem. Sci., 2012,3, 3463-3467

DOI: 10.1039/C2SC21041J
Received 22 Jul 2012, Accepted 29 Aug 2012
First published online 30 Aug 2012
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