Issue 24, 2012

DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications

Abstract

We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic–superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microorganisms can be trapped in the fully isolated microdroplets for high-throughput screening, or in hydrogel micropads for screening in 3D microenvironments.

Graphical abstract: DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications

Supplementary files

Article information

Article type
Paper
Submitted
14 Aug 2012
Accepted
11 Oct 2012
First published
12 Oct 2012

Lab Chip, 2012,12, 5218-5224

DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications

E. Ueda, F. L. Geyer, V. Nedashkivska and P. A. Levkin, Lab Chip, 2012, 12, 5218 DOI: 10.1039/C2LC40921F

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