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Issue 3, 2012
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A novel genetically encoded fluorescent protein as a Cu(I) indicator

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Abstract

We constructed the copper(I)-binding domain of Mycobacterium tuberculosis (Mtb) CDC 1551 (residues 1–162) between cyan fluorescent protein (CFP) and yellow fluorescent protein (YFP), and formed a novel genetically encoded fluorescent copper(I) responsive protein (PMtb). The sensitivity and selectivity to copper(I) of the PMtb was sought. The experiments showed that the copper(I)-binding domain of the PMtb was highly sensitive and selective towards copper(I).

Graphical abstract: A novel genetically encoded fluorescent protein as a Cu(i) indicator

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The article was received on 29 May 2011, accepted on 07 Nov 2011 and first published on 29 Nov 2011


Article type: Communication
DOI: 10.1039/C1DT11002K
Citation: Dalton Trans., 2012,41, 727-729
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    A novel genetically encoded fluorescent protein as a Cu(I) indicator

    X. Yan, X. Li, S. Lv and D. He, Dalton Trans., 2012, 41, 727
    DOI: 10.1039/C1DT11002K

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