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Issue 8, 2012
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Direct characterization of protein oligomers and their quaternary structures by single-molecule FRET

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Abstract

Using a single-molecule method, we directly distinguish among oligomers from monomers to tetramers and determine their quaternary structures. Using this method, we found that RecR forms a stable dimer and its oligomeric form is modulated by its own concentration and the interaction with RecO.

Graphical abstract: Direct characterization of protein oligomers and their quaternary structures by single-molecule FRET

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Publication details

The article was received on 20 Oct 2011, accepted on 23 Nov 2011 and first published on 24 Nov 2011


Article type: Communication
DOI: 10.1039/C2CC16528G
Citation: Chem. Commun., 2012,48, 1138-1140
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    Direct characterization of protein oligomers and their quaternary structures by single-molecule FRET

    C. Kim, J. Y. Kim, S. H. Kim, B. I. Lee and N. K. Lee, Chem. Commun., 2012, 48, 1138
    DOI: 10.1039/C2CC16528G

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