Issue 4, 2013
From the journal:

Chemical Communications

A thermally-stable enzyme detection assay that amplifies signal autonomously in water without assistance from biological reagents†

Kimy Yeung,a   Kyle M. Schmida  and  Scott T. Phillips*a  

* Corresponding authors

a The Pennsylvania State University, 104 Chemistry Bldg., University Park, USA
E-mail: sphillips@psu.edu
Fax: +1 814 865 5235
Tel: +1 814 867 2502

Abstract

This Communication describes a thermally-stable small molecule and a corresponding assay strategy that autonomously amplifies a colorimetric signal when a specific enzyme biomarker is detected.

Graphical abstract: A thermally-stable enzyme detection assay that amplifies signal autonomously in water without assistance from biological reagents

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Article information

DOI
https://doi.org/10.1039/C2CC36861G
Article type
Communication
Submitted
20 Sep 2012
Accepted
01 Nov 2012
First published
05 Nov 2012

Chem. Commun., 2013,49, 394-396

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A thermally-stable enzyme detection assay that amplifies signal autonomously in water without assistance from biological reagents

K. Yeung, K. M. Schmid and S. T. Phillips, Chem. Commun., 2013, 49, 394 DOI: 10.1039/C2CC36861G

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