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Issue 63, 2012
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Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography

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Abstract

A γ-AApeptide-based tracer for positron emission tomography imaging of integrin αvβ3 is reported. Despite its shorter sequence and linear nature, this tracer had comparable integrin αvβ3 binding affinity to the cyclic arginine-glycine-aspartic acid peptide but significantly higher resistance to enzymatic degradation and better stability.

Graphical abstract: Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography

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Publication details

The article was received on 07 Mar 2012, accepted on 10 Jun 2012 and first published on 19 Jun 2012


Article type: Communication
DOI: 10.1039/C2CC33620K
Citation: Chem. Commun., 2012,48, 7850-7852
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    Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography

    Y. Yang, Y. Niu, H. Hong, H. Wu, Y. Zhang, J. W. Engle, T. E. Barnhart, J. Cai and W. Cai, Chem. Commun., 2012, 48, 7850
    DOI: 10.1039/C2CC33620K

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