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Issue 57, 2012
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A rapid and facile signal enhancement method for microcantilever-based immunoassays using the agglomeration of ferromagnetic nanoparticles

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Abstract

A rapid and facile signal enhancement method for detecting alpha-fetoprotein (AFP) was developed using the magnetic agglomeration of ferromagnetic nanoparticles and microcantilever sensors. The resonance frequency and deflection of the cantilevers were found to be more than 10-fold greater than that before physical agglomeration of the free nanoparticles around the magnetized nanoparticles.

Graphical abstract: A rapid and facile signal enhancement method for microcantilever-based immunoassays using the agglomeration of ferromagnetic nanoparticles

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Publication details

The article was received on 03 Apr 2012, accepted on 30 May 2012 and first published on 31 May 2012


Article type: Communication
DOI: 10.1039/C2CC32400H
Citation: Chem. Commun., 2012,48, 7182-7184
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    A rapid and facile signal enhancement method for microcantilever-based immunoassays using the agglomeration of ferromagnetic nanoparticles

    D. Lee, D. Kwon, W. Ko, J. Joo, H. Seo, S. S. Lee and S. Jeon, Chem. Commun., 2012, 48, 7182
    DOI: 10.1039/C2CC32400H

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