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Issue 11, 2011
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Self-assembling drugs: A new therapeutic strategy

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Abstract

In the current work we proposed the new idea of “self-assembled drug” based on the combination of two or more drugs. As model system we used hexadecyldimethylammonium bromide: dicloxacilin at room temperature. The two drugs are well known for their therapeutic effect and together form worm-like micelles with the combined therapeutic effect of both individual compounds. The system was investigated using, density and sound velocity, dynamic light scattering and cryo- electron microscopy (cryo-TEM) and UV for a complete physicochemical and stability characterization.

Graphical abstract: Self-assembling drugs: A new therapeutic strategy

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Publication details

The article was received on 22 Dec 2010, accepted on 31 Mar 2011 and first published on 03 May 2011


Article type: Paper
DOI: 10.1039/C0SM01529F
Citation: Soft Matter, 2011,7, 5194-5199
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    Self-assembling drugs: A new therapeutic strategy

    N. Hassan, J. M. Ruso and A. González-Pérez, Soft Matter, 2011, 7, 5194
    DOI: 10.1039/C0SM01529F

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