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Issue 5, 2011
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Facile one-pot synthesis of polymerphospholipid composite microbubbles with enhanced drug loading capacity for ultrasound-triggered therapy

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Abstract

This paper reports the one-pot synthesis of perfluorocarbon microbubbles with crosslinked shells of poly(acrylic acid) and phospholipid that boast excellent ultrasound contrast enhancement, enhanced loading capacity, and the ability to retain or release their contents through variation in the level of ultrasound exposure.

Graphical abstract: Facile one-pot synthesis of polymer–phospholipid composite microbubbles with enhanced drug loading capacity for ultrasound-triggered therapy

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Publication details

The article was received on 09 Oct 2010, accepted on 03 Jan 2011 and first published on 24 Jan 2011


Article type: Communication
DOI: 10.1039/C0SM01131B
Citation: Soft Matter, 2011,7, 1656-1659
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    Facile one-pot synthesis of polymerphospholipid composite microbubbles with enhanced drug loading capacity for ultrasound-triggered therapy

    M. A. Nakatsuka, J. H. Lee, E. Nakayama, A. M. Hung, M. J. Hsu, R. F. Mattrey, S. C. Esener, J. N. Cha and A. P. Goodwin, Soft Matter, 2011, 7, 1656
    DOI: 10.1039/C0SM01131B

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