Issue 9, 2011

Protein–dendron conjugates for DNA binding: understanding the effect of the protein core on multivalency

Abstract

In this work we have used molecular dynamics simulations to explore the binding between two different protein–dendron conjugates and double stranded DNA. Different protein cores protect the binding site from the external environment, but can also influence the multivalent recognition between the spermine ligands of the dendron and the DNA.

Graphical abstract: Protein–dendron conjugates for DNA binding: understanding the effect of the protein core on multivalency

Supplementary files

Article information

Article type
Communication
Submitted
17 Jul 2011
Accepted
28 Sep 2011
First published
24 Oct 2011

RSC Adv., 2011,1, 1677-1681

Protein–dendron conjugates for DNA binding: understanding the effect of the protein core on multivalency

G. M. Pavan, M. A. Kostiainen and A. Danani, RSC Adv., 2011, 1, 1677 DOI: 10.1039/C1RA00472G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements